FIELD: biotechnology.
SUBSTANCE: present invention relates to biotechnology, molecular biology and medicine. Described is a PaCas9 nuclease enzyme and use of said nuclease enzyme. Invention also relates to a nucleic acid encoding said nuclease, a genetic construct, an expression vector, vector for delivery, which include said nucleic acid, a liposome containing said nuclease or nucleic acid encoding said nuclease, a method of producing nuclease, methods of delivery, as well as a host cell, which includes a nucleic acid encoding said nuclease.
EFFECT: invention extends the range of nucleases.
10 cl, 2 dwg, 4 ex
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