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2 706 702

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IPC

C07F1/08(2006-01-01)

C07F13/00(2006-01-01)

C07F15/06(2006-01-01)

A61K31/28(2006-01-01)

A61K31/295(2006-01-01)

A61K31/30(2006-01-01)

(21) (22)

Application

2019119169, 2019-06-20

(24)

Start date

2019-06-20

(22)

Actual filing date

2019-06-20

(45)

Published

2019-11-20

(72)

Inventor

Shchur Irina ViktorovnaBurgart Yanina ValerevnaShchegolkov Evgenij VadimovichGerasimova Natalya AvenirovnaEvstigneeva Natalya PetrovnaZilberberg Natalya VladimirovnaKungurov Nikolaj VasilevichSaloutin Viktor IvanovichChupakhin Oleg Nikolaevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Organicheskogo Sinteza Im. I.Ya. Postovskogo Uralskogo Otdeleniya Rossijskoj Akademii NaukGosudarstvennoe Byudzhetnoe Uchrezhdenie Sverdlovskoj Oblasti Nauchno-Issledovatelskij Institut Dermatovenerologii I Immunopatologii"

METAL COMPLEXES BASED ON POLYFLUORSALICYLATES AND 1,10-PHENANTHROLINE WITH ANTIBACTERIAL ACTIVITY AND A METHOD FOR PRODUCTION THEREOF Russian patent published in 2019 - IPC C07F1/08 C07F13/00 C07F15/06 A61K31/28 A61K31/295 A61K31/30

Abstract RU 2706702 C1

FIELD: chemistry.

SUBSTANCE: invention relates to new metal complexes based on polyfluorsalicylates and 1,10-phenanthroline of general formula I

R¹=H, M=Cu, L=phen, n= m=1; R¹=F, M=Cu, L=phen, n= m=1; R¹=F, M=Co, L=phen, n=1, m=2; R¹=F, M=Mn, L=phen, n=2, m=2; (I), where R¹= H, F; M = Cu(II), Co(II), Mn(II); L = phen (1,10-phenanthroline), n = 1-2, m = 1-2. Also disclosed is a method for production thereof.

EFFECT: compounds of formula (I) have a wide range of antibacterial activity against infections caused by gonococci and / or Escherichia coli, Citrobacter braakii, Staphylococcus aureus, Serratia marcescens.

2 cl, 3 tbl, 4 ex

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RU 2 706 702 C1

Authors

Shchur Irina Viktorovna

Burgart Yanina Valerevna

Shchegolkov Evgenij Vadimovich

Gerasimova Natalya Avenirovna

Evstigneeva Natalya Petrovna

Zilberberg Natalya Vladimirovna

Kungurov Nikolaj Vasilevich

Saloutin Viktor Ivanovich

Chupakhin Oleg Nikolaevich

Dates

2019-11-20—Published

2019-06-20—Filed