METHOD FOR NON-INVASIVE DIAGNOSIS OF MYOCARDIAL FIBROSIS OF TRANSPLANTED HEART AT A LONG POST-TRANSPLANTATION PERIOD IN RECIPIENTS SUFFERING ACUTE REJECTION Russian patent published in 2019 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely organ transplantation and clinical laboratory diagnostics, and can be used for diagnosis of myocardial fibrosis of transplanted heart at a long post-transplantation period in a recipient suffering acute rejection. That is ensured by diagnosing venous blood plasma concentration of galectin-3 and if its level is higher than 16.9 ng/ml, the presence of transplant fibrosis is diagnosed.

EFFECT: invention provides accessibility and non-invasiveness of diagnostics, reduced time of its carrying out with simultaneous achievement of reliable diagnosis of myocardial fibrosis in the above group of patients, as well as increasing the survival rate of the patients with the transplanted heart and improving the results of the heart transplantation by timely determination of the indications to the unscheduled endomyocardial biopsy.

1 cl, 2 ex