FIELD: medicine.
SUBSTANCE: invention relates to ophthalmology and can be used for diagnosing compression optical neuropathy (CON) in a chiasmo-sellar region (CSR) pathology. An optical coherence tomography (OCT) with an angiography function is performed on Cirrus HD-OCT 5000 AngioPlex™ instrument. At that, according to “Macular Cube 512×128” define an index of thickness of retinal macular area as distance from internal boundary membrane to retinal pigment epithelium on 4 sectors – upper, nasal, lower, temporal, in ring zone with outer diameter of 6 mm and inner diameter of 3 mm, with center located in foveal area. Using the “Ganglion Cell Analysis” program using the “Macular Cube 512×128” protocol define the thickness of the macular complex, including a layer of retinal ganglion cells and an internal plexiform layer, its average value and in 6 sectors – upper, upper nasal, lower nasal, lower, lower temporal, upper temporal. According to the protocol “Angiography 6×6 mm” is the vascular density (VD) index – average and in the ring zone with an external diameter of 3 mm and an inner diameter of 1 mm with a center in the foveal region. According to “ONH Angiography 4.5×4.5 mm” is used to define a capillary flow index (CFI) in 4 sectors – upper, nasal, lower, temporal, in a ring zone with an external diameter of 6 mm and an internal diameter of 2 mm with a center in the optic nerve disc area. Results of analysis are analyzed. If it is detected that at least one eye: a retina thickness in the macular area in the nasal sector of the external ring is less than 290 mcm, the thickness of the macular complex is medium and in the upper nasal sector less than 80 mcm, indices of thickness of macular complex in upper and lower nasal sectors less than 79 mcm, indices of VD – medium and in zone of internal ring less than 19 mm/mm2, CFI in lower sector is less than 0.45, then CON is diagnosed in CSR pathology.
EFFECT: method provides timely detection of optic nerve compression in the course of CSR pathology, reduced labor intensity of diagnosing by determining OCT values with angiography function.
1 cl, 2 ex
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Authors
Dates
2020-02-07—Published
2019-04-18—Filed