METHOD FOR DETERMINING MAXIMUM CONCENTRATION TIME OF PHOTOSENSITIZER CHLORIN E6 LYSINE DIMEGLUMINE SALT IN TUMOR Russian patent published in 2020 - IPC A61B6/00 A61K49/00 A61K31/409 A61N5/06 A61P35/00 

Abstract RU 2713941 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used to determine time of reaching maximum concentration of photosensitizer (PS) of chlorine series – chlorine e6 lysine dimeglumine salt in body tissues after its introduction. PS chlorin e6 lysine dimeglumine salt is introduced into the body. 30 minutes after the PS administration, a tumor / standard fluorescent contrast value is calculated. If the tumor / standard fluorescent contrast is up to 3.0, the maximum PS accumulation in the tumor is considered to be 3 hours from the moment of PS administration, with the tumor / standard fluorescent contrast more than 3.0–4 hours.

EFFECT: method provides higher clinical effectiveness ensured by possibility of individual determination of time of maximum accumulation of PS chlorine e6 dimeglumine salt in tumors.

1 cl, 3 ex

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RU 2 713 941 C2

Authors

Kaprin Andrej Dmitrievich

Filonenko Elena Vyacheslavovna

Negrimovskij Vladimir Mikhajlovich

Kazachkina Natalya Ivanovna

Grigorevykh Nadezhda Igorevna

Dates

2020-02-11Published

2019-09-12Filed