METHOD OF PHOTODYNAMIC THERAPY OF GROWTH SURFACE SOLID CONNECTIVE-TISSUE SARCOMA OF M-1 RATS Russian patent published in 2019 - IPC A61N5/67 A61K31/409 A61K47/22 A61P35/00 G09B23/28 

Abstract RU 2704202 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental medicine and oncology, and can be used for photodynamic therapy of transplanted superficial solid connective tissue sarcoma M-1 of rats. That is ensured by introducing a photosensitizer "Photoran E6" in doses of 5.0 mg/kg, which when extrapolated to a human dose is 0.85 mg/kg of patient's body weight. 2.5 hours after the photosensitizer is introduced, the laser is irradiated at wave length 660–670 nm with power density 250 mW/cm2 and energy density of 300 J/cm2 laser radiation, exposure time – 20 minutes.

EFFECT: method provides higher effectiveness of photodynamic therapy, longer life and 100 % complete cure of animals due to optimally selected parameters and mode of laser exposure and dose of the introduced photosensitizer.

1 cl, 2 tbl, 3 dwg

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RU 2 704 202 C1

Authors

Abramova Olga Borisovna

Drozhzhina Valentina Vladimirovna

Kaplan Mikhail Aleksandrovich

Dates

2019-10-24Published

2019-07-03Filed