FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to the use of Lysylendopeptidase Lys-C from Lysobacter enzymogenes in the processing of botulinum neurotoxin of serotype F (BoNT/F).
EFFECT: use of Lys-C for proteolytic splitting of single-stranded BoNT/F enables to obtain an active double-stranded BoNT/F.
9 cl, 11 dwg, 2 tbl, 8 ex
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Authors
Dates
2020-04-17—Published
2018-11-19—Filed