METHODS FOR PRODUCING PROTEOLYTICALLY PROCESSED POLYPEPTIDES Russian patent published in 2020 - IPC C07K14/33 C12N15/09 C12N9/52 A61K38/43 A61P7/02 

Abstract RU 2719164 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to the use of Lysylendopeptidase Lys-C from Lysobacter enzymogenes in the processing of botulinum neurotoxin of serotype F (BoNT/F).

EFFECT: use of Lys-C for proteolytic splitting of single-stranded BoNT/F enables to obtain an active double-stranded BoNT/F.

9 cl, 11 dwg, 2 tbl, 8 ex

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RU 2 719 164 C1

Authors

Rummel, Andreas

Dates

2020-04-17Published

2018-11-19Filed