FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to a proteolytically active polypeptide which is capable of hydrolysing botulinic neurotoxin A (BoNT/A) to produce double-stranded botulinum neurotoxin A (BoNT/A).
EFFECT: proteolytically active polypeptide comprising an amino acid sequence having at least 95 % sequence identity of SEQ ID NO: 1 can be used to produce a biologically active double-stranded BoNT/A.
11 cl, 11 dwg, 2 tbl, 8 ex
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|---|---|---|---|
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|
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|
RU2831112C2 |
| THERAPEUTIC AND COSMETIC USE OF SEROTYPE E NEUROTOXIN BOTULINUM | 2019 |
|
RU2800604C2 |
| BOTULINUM NEUROTOXIN BIOHYBRID | 2019 |
|
RU2816855C2 |
