METHOD FOR SYNTHESIS OF MOLECULES CONTAINING A FUNCTIONAL GROUP OF NITRILOXIDE Russian patent published in 2020 - IPC C07D233/34 

FIELD: chemistry.

SUBSTANCE: invention relates to a synthesis of a compound of formula (I), which after reacting with the polymer and mixing with the filler cannot form covalent bonds with the filler and, therefore, does not cause too high viscosity increase of mixture. Method includes two consecutive steps (b1) and (b2) in compliance with the principles of single-reactor synthesis. Step (b1) comprises reacting a compound of formula (II) with a compound of formula (III) in the presence of at least one polar solvent S₁, at least one base at temperature T₁ from 70 to 150 °C to form ether. At step (b2), said ether is reacted with an aqueous solution of hydroxylamine at temperature T₂ from 30 to 70 °C to obtain an oxime compound of formula (IV). Then at step (c), said oxime compound of formula (IV) is separated, and at step (d) oxidising oxime compound of formula (IV) with an oxidant in the presence of at least one organic solvent S₂. In said formulas group is group , in which X is selected from an oxygen atom and a sulfur atom ; R₁ is C₁-C₁₂ alkyl group or an OR' group, where R' is C₁-C₁₂ alkyl group; n is integer from 0 to 4; Sp is a linear or branched C₁-C₂₄ alkylene chain optionally interrupted by one or more nitrogen or oxygen atoms; Z is nucleofuge.

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EFFECT: disclosed method simplifies processing of effluents and reduces production costs without detriment to yield and purity of the product.

24 cl, 3 ex