METHOD FOR DETERMINING A RISK OF DEVELOPING A CEREBROVASCULAR PATHOLOGY IN MYELOPROLIFERATIVE DISEASES Russian patent published in 2020 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to neurology, hematology, and discloses a method for determining a risk of developing a cerebrovascular pathology in myeloproliferative diseases. Method is characterized by the fact that complex assessment of risk biomarkers and their parameters is carried out: blood fibrinolytic activity is determined, fibrinolysis index, von Willebrand factor, hemoglobin level, hematocrit level, erythrocyte deformability, strength of erythrocyte aggregates, as well as taking account of the presence of the previous cerebral circulation disorder, the V617F mutation in the Jak2 gene, cephalalic syndrome more often than once a week, arterial and venous thrombosis in anamnesis and presence of focal brain changes of vascular genesis according to MRI data.

EFFECT: invention provides high reliability of evaluation and can be used to determine a risk of developing a cerebrovascular pathology in myeloproliferative diseases (MPD).

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