NEUTRON CAPTURE THERAPY SYSTEM AND TARGET FOR BEAM PARTICLE GENERATION DEVICE Russian patent published in 2020 - IPC A61N5/10 

Abstract RU 2727576 C1

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment. Neutron capture therapy system comprises: a neutron generation device comprising an accelerator and a target, in which a beam of charged particles generated during acceleration in an accelerator interacts with a target for generating a neutron beam, as well as a beam forming assembly. Target comprises: an active layer for interaction with a beam of charged particles for generation of a neutron beam, a support layer for supporting the active layer and a heat-dissipating layer, which includes a tubular element containing tubes located next to each other. Beam forming assembly comprises: a retarder for slowing down the neutron generated in the target to energy of the epithermal neutron energy range, a reflector enclosing the retarder, wherein the reflector directs the diverting neutron back to the retarder to increase the intensity of the epithermal neutron beam, thermal neutron absorber configured to absorb thermal neutrons in order to avoid overdose in the superficial healthy tissue during therapy, a radiation shield located in the rear part of the reflector around the output of the beam for screening of leaky neutrons and photons in order to reduce the dose for healthy tissue in the non-irradiated region, as well as the output of the beam. At that, outline of outer surface of tubular element connected to support layer or active layer has shape of arc, wherein the active layer on each tube of the tubular member covers at least 1/4 of the outer circumference of the tube. Target for particle beam generation device comprises: active layer for generation of particle beam, support layer for active layer support, and heat-dissipating layer, including tubular element containing tubes located next to each other, wherein the outline of the outer surface of the tubular element lateral part, which is connected to the support layer or the active layer, has an arc shape, wherein the active layer on each tube of the tubular element covers at least 1/4 of the outer circumference of the tube. Neutron capture therapy system comprises: a neutron generation device comprising an accelerator and a target, in which a beam of charged particles generated during acceleration in an accelerator interacts with a target for generating a neutron beam. Target comprises: cooling inlet, cooling outlet and cooling channel arranged between cooling inlet and cooling outlet, wherein in cooling channel there is at least one protruding section and protruding section comprises cooling surface; and beam forming unit. Beam forming assembly comprises: retarder for decelerating neutron generated in target to energy of epithermal neutron energy range, reflector surrounding retarder, wherein deflector directs deflecting neutron back to retarder to increase intensity of epithermal neutron beam, thermal neutron absorber configured to absorb thermal neutrons in order to avoid overdose in superficial healthy tissue during therapy, a radiation shield installed in the rear part of the reflector around the output of the beam for screening of leaky neutrons and photons in order to reduce the dose for healthy tissue in the non-irradiated region, as well as the output of the beam. Target for device for generation of particle beam includes: active layer for generation of particle beam, support layer for support of active layer, and heat-dissipating layer, which includes cooling channel, along which cooling medium circulates. In cooling channel there is at least one protruding section and protruding section comprises cooling surface. Target for device for generation of neutron beam comprises: active layer for interaction with incident particle beam for generation of neutron beam, at that active layer contains first active layer and the second active layer and the incident particle beam sequentially penetrate through the first active layer and the second active layer in the falling direction, and a support layer for suppressing swelling induced by the incident particle beam and for supporting the active layer. Neutron capture therapy system comprises: a neutron generation device comprising an accelerator and a target in which a beam of charged particles generated during acceleration in an accelerator interacts with a target for generating a neutron beam, a beam forming assembly. Beam forming assembly comprises: retarder for decelerating neutron generated in target to energy of epithermal neutron energy range, reflector enclosing retarder, wherein deflector directs deflecting neutron back to retarder to increase intensity of epithermal neutron beam, thermal neutron absorber designed to absorb thermal neutrons in order to avoid overdose in superficial healthy tissue during therapy, a radiation shield located in the rear part of the reflector around the output of the beam for screening of leaky neutrons and photons in order to reduce the dose for healthy tissue in the non-irradiated region, as well as the output of the beam.

EFFECT: technical result of claimed invention consists in improvement of cooling efficiency.

31 cl, 7 dwg, 3 tbl

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RU 2 727 576 C1

Authors

Lyu Yuan-Khao

Tsaj Tszyun-Ven

Chen Vej-Lin

Dates

2020-07-22Published

2017-07-13Filed