RADIATION DETECTION SYSTEM FOR NEUTRON CAPTURE THERAPY SYSTEM AND METHOD OF RADIATION DETECTION Russian patent published in 2019 - IPC A61N5/10 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medical equipment, specifically to radiation detection means in neutron capture therapy. Radiation detection system for a neutron capturing therapy system comprises a charged particle beam, a charged particle beam inlet configured to transmit a beam of charged particles, a neutron generation module, generating neutron beam after nuclear reaction between neutron generation module and charged particles beam, beam former used to adjust the flow and quality of the neutron beam generated by the neutron generation module and the beam output adjacent to the neutron generation module, wherein the radiation detection system comprises a radiation detection device used for real-time detection γ-rays, instantly emitted during neutron beam emission, and is configured to calculate the boron concentration value from the detected signal γ, wherein boron concentration is calculated by formula A: B(t)=GC(t)/k (Formula A), where B(t) is boron concentration at time t, unit B(t) is ppm (millionth fraction), unit of time t is second, k is measured value, GC(t) is value obtained after number of background γ subtracted from total γ preset energy zone detected during t, wherein k is calculated by formula B: k=GC(t₀)/B(t₀) (Formula B), where B(t₀) is boron concentration at time t₀, unit B(t₀) is ppm, unit of time t₀ is second, GC(t₀) is a value obtained after the number of background γ subtracted from total γ preset energy zone detected during t₀, wherein B(t₀) is calculated by formula C: B(t₀)=B_blood(t₀)×R_T/N (Formula C), where B_blood(t₀) is blood boron concentration measured during t₀, unit B_blood(t₀) is ppm, and R_T/N is a ratio of boron concentration, which can be obtained based on PET or experimental data or on a theoretical basis, to boron concentration in normal tissue. Method of detecting radiation is carried out using a detection system. Neutron-capture therapy system comprises a beam radiation detection system and is configured to correct a non-linear relationship between boron concentration and tumor dose, calculating boron concentration from a detected signal γ, calculating the tumor dose from the boron concentration and correcting the non-linear relationship between the boron concentration and the tumor dose when calculating the tumor dose.

EFFECT: use of inventions makes it possible to increase the radiation dose accuracy.

8 cl, 7 dwg