FIELD: biotechnology.
SUBSTANCE: invention relates to the biotechnology. Disclosed is a method of testing substances affecting aging processes by analysing patient's blood. Method involves producing patient's mononuclear cells by standard venous blood sampling with subsequent isolation of mononuclear leukocyte (MNC) population, incubation of the patient's MNC culture with the recommended doses of the test agent and determining the ratio of cells in different phases of the cell cycle by flow cytometry in the MNC culture. That is followed by evaluating the obtained results using the difference in cell ratio distribution on the cell cycle.
EFFECT: method provides the possibility of testing the activity of substances and preparations aimed at treating various pathologies, including those associated with age.
1 cl, 1 tbl, 4 ex
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|---|---|---|---|
| METHOD OF OBTAINING PEPTIDES THAT INDUCE OWN STEM CELLS | 2022 |
|
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|
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| METHODS FOR DIAGNOSING AND INDUCING LEUKAEMIA/LYMPHOMA | 2010 |
|
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|
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| BIOMEDICAL CELL PREPARATION | 2017 |
|
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| METHOD FOR EVALUATION OF STRONTIUM IMPACT ON APOPTOSIS, ASSOCIATED WITH ALLELLIC VARIANTS OF FAS GENE IN CHILDREN | 2016 |
|
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| METHOD OF MODIFICATION OF PERIPHERAL BLOOD MONOCYTES TO INCREASE THEIR PARACRINE ACTIVITY DURING AUTOLOGOUS TRANSPLANTATION | 2012 |
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| METHOD FOR PREPARING AUTOLOGOUS TUBERCULOSIS VACCINE | 2008 |
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|
RU2636220C2 |
