15-AROYL-2-HYDROXY-5,5-DIMETHYL-2,3,5,6-TETRAHYDRO-1H-2,7B-METHANOBENZO[5,6][1,4]DIAZEPINO[1,7-A]QUINOXALINE-1,7,8(4H, 9H)TRIONS, HAVING ANTI-INFLAMMATORY ACTIVITY Russian patent published in 2020 - IPC C07D487/08 A61P29/00 

Abstract RU 2729185 C1

FIELD: chemistry.

SUBSTANCE: invention relates to 15-aroyl-2-hydroxy-5,5-dimethyl-2,3,5,6-tetrahydro-1H-2,7b-methanobenzo[5,6][1,4]diazepino[1,7-a]quinoxaline-1,7,8(4H, 9H) to trions of general formula given below, where Ar=4-ClC6H4, R=H (Ia); Ar=C6H5, R=CH2C6H5 (Ib); Ar=C6H5, R=2,4-diFC6H4 (Ic).

EFFECT: compounds Ia-c have anti-inflammatory activity.

1 cl, 2 tbl, 4 ex

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RU 2 729 185 C1

Authors

Apushkin Danila Yurevich

Andreev Aleksandr Igorevich

Mashevskaya Irina Vladimirovna

Prikhodko Yaroslav Igorevich

Dates

2020-08-05Published

2019-11-19Filed