FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to new individual compounds of azapentacycloeicosanes class. Invention describes 20-aroyl-12-hydroxy-17,17-dimethyl-3-phenyl3,10,13-triazapentacyclo[10.7.1.01,10.O4,9.O14,19]eicosa-4,6,14(19)-2,11,15-triones of the formula:
wherein R means hydrogen atom; Ar means phenyl; or R means benzyl and Ar means p-methoxyphenyl group. Also, the invention describes a method for preparing these compounds. Invention provides preparing new compounds that can be used as the parent substances for synthesis of new heterocyclic systems.
EFFECT: improved preparing method, valuable chemical properties of compounds.
4 cl, 1 tbl, 3 ex
Title |
Year |
Author |
Number |
15-AROYL-2-HYDROXY-5,5-DIMETHYL-2,3,5,6-TETRAHYDRO-1H-2,7B-METHANOBENZO[5,6][1,4]DIAZEPINO[1,7-A]QUINOXALINE-1,7,8(4H, 9H)TRIONS, HAVING ANTI-INFLAMMATORY ACTIVITY |
2019 |
- Apushkin Danila Yurevich
- Andreev Aleksandr Igorevich
- Mashevskaya Irina Vladimirovna
- Prikhodko Yaroslav Igorevich
|
RU2729185C1 |
ANALGESIC MEDICATION |
2007 |
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
- Fedorovtseva Anastasija Nikolaevna
|
RU2360914C1 |
1,1'-DIARYL-3'-AROYL-4'-HYDROXY-1H-SPIRO [INDENO[1,2-b]PYRROL-3,2'-PYRROL]-2,4,5'-(1'H)-TRIONES AND METHOD OF THEIR OBTAINING |
2011 |
- Bubnov Nikolaj Vladimirovich
- Denislamova Ekaterina Sergeevna
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467011C1 |
METHOD FOR PRODUCING (R*)-3-AROYL-2-HYDROXY-2-((S*)-2-OXOCYCLOALKYL)PYRROLO[1,2-A]QUINOXALINE-1,4(2H,5H)-DIONES |
2018 |
- Maslivets Andrej Nikolaevich
- Kasatkina Svetlana Olegovna
- Stepanova Ekaterina Evgenevna
- Balandina Svetlana Yurevna
|
RU2665060C1 |
INTERMEDIATE PRODUCTS - METHYL 7-ARYL-4, 9-DIAROYL-3-HYDROXY-1-(2-HYDROXYPHENYL)-2,6-DIOXO-1, 7-DIAZASPIRO[4,4]NONE-3, 8-DIENE-8-CARBOXYLATES; METHYL 6, 9-DIARYL-11-AROYL-2-(O-HYDROXYPHENYL)-3, 4,10-TRIOXO-7-OXA-2, 9-DIAZATRICYCLO[6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATES; METHOD OF PRODUCING METHYL 6, 9-DIARYL-11-AROYL-2-(O-HYDROXYPHENYL)-3, 4, 10-TRIOXO-7-OXA-2, 9-DIAZATRICYCLO [6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATES; METHYL 11-BENZOYL-2-O-HYDROXYPHEHYL-3, 4, 10-TRIOXO-9-P-TOLYL-6-PHENYL-7-OXA-2, 9-DIAZATRICYCLO [6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATE HAVING ANTIMICROBIAL ACTIVITY |
2008 |
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Aleksandrova Galina Arsent'Evna
|
RU2383550C1 |
ISOPROPYL-12-AROYL-2-HYDROXY-1,6-DIOXO-4-(3-PYRIDINYL)-7-PHENYL-1,3,6,7-TETRAHYDRO-2,5α-METHANO[1,4]DIAZEPINO[1,7α]-QUINOXALINE-5-CARBOXYLATES AND METHOD FOR THEIR PREPARING |
2006 |
- Bozdyreva Ksenija Sergeevna
- Maslivets Andrej Nikolaevich
- Aleksandrova Galina Arsent'Evna
|
RU2304581C1 |
METHOD OF OBTAINING 1,2-DIHYDRO-3H-PYRIMIDO[1,6-A]QUINOXALINE-3,5(6H)-DIONES |
2018 |
- Maslivets Andrej Nikolaevich
- Kasatkina Svetlana Olegovna
- Stepanova Ekaterina Evgenevna
- Makhmudov Ramiz Ragibovich
|
RU2676682C1 |
METHYL 11-ARYL-12-AROYL-9-HYDROXY-4,6-DIMETHYL-3,5,10-TRIOXO-4,6,8,11-TETRAAZATRICYCLO[7,2,1,0]DODEC-2(7)-ENE-1-CARBOXYLATES AND SYNTHESIS METHOD THEREOF |
2008 |
- Denislamova Ekaterina Sergeevna
- Maslivets Andrej Nikolaevich
|
RU2383549C1 |
6,6-DIMETHYL-8-OXO-5,6,8,9-TETRAHYDROBENZO[F]-PYRROLO[2,1-ALPHA]ISOQUINOLINE-9-SPIRO-2-(3-AROYL-4-HYDROXY-1-O-HYDROXYPHENYL-5-OXO-2,5-DIHYDRO-1H-PYRROLES) AND 6,6-DIMETHYL-8-OXO-5,6,8,9-TETRAHYDROBENZO[F]PYRROLO[2,1-ALPHA]ISOQUINOLINE-9-SPIRO-2-(3-BENZOYL-4-HYDROXY-1-O-HYDROXYPHENYL-5-OXO-2,5-DIHYDRIO-1H-PYRROLE) ELICITING ANALGESIC ACTIVITY AND METHOD FOR THEIR PREPARING |
2006 |
- Anikina Lada Vladimirovna
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
|
RU2316557C1 |
METHYL 1-ARYL-3-HYDROXY-3'-METHYL-2,4,5'-TRIOXO-6-PHENYL-2,4,5,6-TETRAHYDRO-5'H-SPIRO[INDOLE-7,4'-ISOXAZOLE]-7a(1H)-CARBOXYLATES, METHYL 1-ARYL-(1'-PHENYL AND 1'-BENZYL)-3-HYDROXY-3'-METHYL-2,4,5'-TRIOXO-6-PHENYL-1',2,4,5,5',6-HEXAHYDROSPIRO[INDOLE-7,4'-PYRAZOLE]-7a(1H)-CARBOXYLATES AND METHYL 1'-ARYL-3'-HYDROXY-1,2',3,4'-TETRAOXO-6'-PHENYL-1,2',3,4',5',6'-HEXAHYDROSPIRO[INDENE-2,7'-INDOLE]-7a'(1'H)-CARBOXYLATES, DEMONSTRATING ANALGESIC ACTIVITY AND METHOD FOR OBTAINING THEREOF |
2014 |
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2577528C2 |