METHOD FOR PREVENTING PRECANCER RECURRENCE AND PRIMARY CERVICAL CANCER FOLLOWING ORGAN-PRESERVING TREATMENT BY DIAGNOSING AND TREATING HPV IN ANOGENITAL-OROPHARYNGEAL SPHERE IN SEXUAL PAIRS Russian patent published in 2020 - IPC A61K31/7076 A61P35/00 

Abstract RU 2733934 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine. What is presented is a method for prevention of recurrent pre-cancer and primary cervical cancer following an organ-preserving treatment by diagnosing and treating human papilloma virus (HPV) in anogenital-oropharyngeal sphere in sexual pairs. If the HPV gene is identified in women in scrapings from the cervix uteri stump and viral load is <3 lg/105, then antiviral therapy is carried out by immunomodulator isoprenosine pranobex 500 mg in dose of 50 mg/kg of body weight in 3-4 doses for 28 days in the form of monotherapy with subsequent evaluation of antiviral effect in 3 and 6 months. If >3 lg/105 <5 lg/105, >5 lg/105, then electro-, laser- or radio-wave destruction of pathological centers with the above antiviral therapy is performed. If the male is infected with HPV, the treatment is carried out depending on the clinical form of the papilloma virus infection and the result of the cytological examination.

EFFECT: invention provides reducing the risk of developing HPV-associated recurrent pre-cancer and primary cervical cancer.

4 cl, 2 dwg, 2 ex

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RU 2 733 934 C2

Authors

Trushina Olga Ivanovna

Novikova Elena Grigorevna

Apolikhin Oleg Ivanovich

Sivkov Andrei Vladimirovich

Efremov Evgenii Aleksandrovich

Kaprin Andrei Dmitrievich

Kostin Andrei Aleksandrovich

Dates

2020-10-08Published

2020-04-15Filed