METHOD FOR DETERMINING ENDOTYPES OF ATOPIC BRONCHIAL ASTHMA IN CHILDREN AND ADOLESCENTS 5 TO 12 YEARS OLD Russian patent published in 2020 - IPC A61B5/08 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to pediatrics and pulmonology, and can be used for determining the bronchial asthma endotype in children aged 5 to 12 years. Such spirometry indices as forced exhalation volume in the first second (FEV1) and peak expiratory flow (PEF) are analyzed. Concentration of nitrogen oxide (FeNO_ex) is measured. Method comprises assessing the physical state of the patients by determining a body weight index (BWI) and assessing the quality of life on a questionnaire for percentage deviation of quality of life PDQL after treatment. Patient's sensitivity to drug-induced treatment by inhaled glucocorticosteroid hormones (iGCS) and long-acting beta-agonists (LABA) in pharmacotherapy, after which endotype of atopic bronchial asthma of E_BA is determined by original design formula. If the sum of E_BA is 5 or less, bronchial asthma 1 endotype is determined, if the E_BA in total of 6–10 points, endotype 2 is determined, if the E_BA in total of 11–15 points, endotypes 3 are determined.

EFFECT: method enables detecting patients with certain BA endotypes, improving diagnosis, improving the reliability of treating patients with atopic asthma, and improving the patients' quality of life.

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