FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention refers to using the compound of formula (I) or its pharmaceutically acceptable salts for treating chronic anxiety or acute anxiety. In formula (I), R1 is -F, -Cl, -Br, -I, -OCF3, -OCHF2, -OCH2F, -CF3, -CHF2, -CH2F, -CH3, -CH3CH2, -CF3CH2; R2 is H, C1-C10alkyl with straight chain, branched C3-C10alkyl, cyclic C3-C10alkyl, C1-C10hydroxyalkyl; each of R3 or R4 independently represents H, OH, OR5, F, Cl, Br, I, C1-C10alkyl with straight chain, branched C3-C10alkyl, CF3, CHF2, CH2F, OCF3, OCHF2, OCH2F; or R3 and R4 are bonded to form -OCH2O- or -OCH2CH2O-; R5 is C1-C10 alkyl with straight chain, branched C3-C10alkyl, cyclic C3-C10alkyl or C1-C10hydroxyalkyl; n is 1 or 3, and link -(C2-C3)n- contains at least one single carbon-carbon bond or one double carbon-carbon bond; X is =O, H; Y is NR6; R6 is a straight chain H, C1-C10hydrocarbon, branched C3-C10hydrocarbon, cyclic C3-C10hydrocarbon or aromatic C6-C10hydrocarbon.
(I)
EFFECT: what is presented is using the compound for treating chronic anxiety or acute anxiety.
5 cl, 2 tbl, 2 ex
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Authors
Dates
2020-12-15—Published
2017-01-20—Filed