USING THE COMPOUND FOR TREATING CHRONIC ANXIETY OR ACUTE ANXIETY Russian patent published in 2020 - IPC C07C235/34 C07C235/46 C07D295/185 C07D295/192 C07D317/58 C07D317/60 C07D317/68 A61K31/165 A61K31/166 A61K31/357 A61K31/36 A61K31/4453 A61K31/4525 A61K31/496 A61P25/22 

Abstract RU 2738648 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to using the compound of formula (I) or its pharmaceutically acceptable salts for treating chronic anxiety or acute anxiety. In formula (I), R1 is -F, -Cl, -Br, -I, -OCF3, -OCHF2, -OCH2F, -CF3, -CHF2, -CH2F, -CH3, -CH3CH2, -CF3CH2; R2 is H, C1-C10alkyl with straight chain, branched C3-C10alkyl, cyclic C3-C10alkyl, C1-C10hydroxyalkyl; each of R3 or R4 independently represents H, OH, OR5, F, Cl, Br, I, C1-C10alkyl with straight chain, branched C3-C10alkyl, CF3, CHF2, CH2F, OCF3, OCHF2, OCH2F; or R3 and R4 are bonded to form -OCH2O- or -OCH2CH2O-; R5 is C1-C10 alkyl with straight chain, branched C3-C10alkyl, cyclic C3-C10alkyl or C1-C10hydroxyalkyl; n is 1 or 3, and link -(C2-C3)n- contains at least one single carbon-carbon bond or one double carbon-carbon bond; X is =O, H; Y is NR6; R6 is a straight chain H, C1-C10hydrocarbon, branched C3-C10hydrocarbon, cyclic C3-C10hydrocarbon or aromatic C6-C10hydrocarbon.

(I)

EFFECT: what is presented is using the compound for treating chronic anxiety or acute anxiety.

5 cl, 2 tbl, 2 ex

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RU 2 738 648 C2

Authors

Han, Min

Ma, Xiaohui

Zhou, Wangyi

Liu, Yanyong

Li, Yanchuan

Wang, Jing

Zhou, Shuiping

Sun, He

Zhu, Yonghong

Dates

2020-12-15Published

2017-01-20Filed