METHOD FOR PREDICTION OF THE RISK OF DEVELOPING PREECLAMPSIA IN WOMEN WITHOUT AN AGGRAVATED FAMILY HISTORY TAKING INTO ACCOUNT GENETIC FACTORS Russian patent published in 2020 - IPC G01N33/50 C12Q1/6827 

Abstract RU 2738675 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Disclosed is a method for prediction of the risk of developing preeclampsia in females of Russian nationality, native to Central Black Earth Region, not having an aggravated family history of pre-eclampsia, involving DNA recovery from peripheral venous blood and analysis of polymorphism of the progesterone receptor gene (PGR). If observing the allele T of polymorphous locus rs1042838 of the PGR gene, a high risk of developing preeclampsia is predicted.

EFFECT: invention provides the criteria for assessing the risk of developing preeclampsia from data on genetic polymorphism rs1042838 of the PGR gene in females of Russian nationality, which are native to the Central Black Earth Region and do not have a family history of pre-eclampsia.

1 cl, 1 dwg, 1 tbl, 3 ex

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RU 2 738 675 C1

Authors

Churnosov Mikhail Ivanovich

Golovchenko Oleg Vasilevich

Abramova Mariya Yurevna

Ponomarenko Irina Vasilevna

Dates

2020-12-15Published

2020-07-28Filed