FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to hematology, and aims at predicting the course of nodular sclerosis of Hodgkin lymphoma (HL). After lymphadenectomy in histological sections of lymphoid organ, immunohistochemical staining is carried out and relative quantity of CD163+ and CD68+ macrophages in lymph nodes is calculated morphometrically by formulas S1=D1/n×100% and S2=D2/n×100%. Percentage score PS of these cells is determined by formula PS=(S1+S2)/2. If the PS values are less than or equal to 12.0%, the favorable course of nodular sclerosis HL is stated, and if more than 12.0% the unfavorable course of the disease is stated.
EFFECT: invention provides effective prediction of clinical course of nodular sclerosis HL after lymphadenectomy.
1 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR MORPHOMETRIC ESTIMATION OF THE PROGNOSIS OF THE COURSE OF DIFFUSE LARGE B-CELL LYMPHOMA BY THE INDEX OF THE PROPORTION OF TUMOUR CELLS EXPRESSING PSTAT3 AND PAKT1 IN LYMPH NODES | 2021 |
|
RU2767693C1 |
| METHOD OF MORPHOMETRIC PREDICTION OF COURSE OF DIFFUSE LARGE B-CELL LYMPHOMA BASED ON CONTENT OF p16INK4A- AND p14ARF-POSITIVE TUMOUR CELLS IN LYMPH NODES | 2023 |
|
RU2814849C1 |
| METHOD FOR MORPHOMETRIC PREDICTION OF THE COURSE OF DIFFUSE LARGE B-CELL LYMPHOMA BY THE CONTENT OF P14ARF-POSITIVE TUMOR CELLS IN THE LYMPH NODES | 2022 |
|
RU2785907C1 |
| METHOD FOR MORPHOMETRIC ASSESSMENT OF A DIFFUSE B-LARGE-CELL LYMPHOMA PREDICTION BY STAT3+ TUMOR CELL COUNT IN LYMPH NODES | 2018 |
|
RU2694838C1 |
| METHOD OF OPTIMISATION OF HODGKIN'S LYMPHOMA OF IIIA STAGE TREATMENT IN ADULTS | 2009 |
|
RU2400266C1 |
| METHOD FOR OPTIMISATING TREATMENT OF IIIB-STAGE HODGKIN'S LYMPHOMA OF IN ADULTS | 2008 |
|
RU2364426C1 |
| METHOD OF MORPHOMETRIC PREDICTION OF THE COURSE OF DIFFUSE LARGE B-CELL LYMPHOMA BASED ON THE CONTENT OF AIF-POSITIVE TUMOR CELLS IN THE LYMPH NODES | 2023 |
|
RU2798958C1 |
| METHOD FOR PREDICTION OF EARLY RECURRENCE IN PATIENTS WITH CLASSICAL HODGKIN'S LYMPHOMA | 2019 |
|
RU2702360C1 |
| METHOD FOR TREATING PATIENTS FOR MALIGNANT LYMPHOMAS WITH RADIATION | 2004 |
|
RU2278707C2 |
| METHOD FOR DETERMINING PSEUDO-VESSELS FORMED BY MACROPHAGES IN CHOROIDAL MELANOMA DURING A LIFETIME PATHOLOGIC-ANATOMICAL EXAMINATION | 2022 |
|
RU2790775C1 |
