METHOD FOR MORPHOMETRIC ASSESSMENT OF A DIFFUSE B-LARGE-CELL LYMPHOMA PREDICTION BY STAT3+ TUMOR CELL COUNT IN LYMPH NODES Russian patent published in 2019 - IPC G01N33/53 

Abstract RU 2694838 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to hematology, and can be used for morphometric assessment of prediction of diffuse B-large-cell lymphoma (DBLCL). That is ensured by determining STAT3+ tumor cell count in the lymph nodes. Lymphadenectomy in histological sections of the lymphoid organ is followed by immunohistochemical staining and the relative number of STAT3+ tumor cells in the lymph node in % is measured morphometrically. If the relative number of STAT3+ tumor cells is less than 66 %, a favorable course of diffuse B-large-cell lymphoma is stated. If the disease is equal or more than 66 %, an unfavorable course of the disease is stated.

EFFECT: invention allows predicting the flow DBLCL in patients after lymphadenectomy.

1 cl, 3 ex

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RU 2 694 838 C1

Authors

Dyakonov Dmitrij Andreevich

Rosin Vitalij Anatolevich

Vaneeva Elena Viktorovna

Samarina Svetlana Valerevna

Dates

2019-07-17Published

2018-12-18Filed