SARS-COV-2 REPLICATION INHIBITOR BASED ON A WATER EXTRACT OF THE FUNGUS INONOTUS OBLIQUUS Russian patent published in 2021 - IPC A61K36/06 B01D11/02 A61P31/14 

Abstract RU 2741714 C1

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to the pharmaceutical industry and namely to the use of an extract of the basidial fungus Inonotus obliquus to inhibit the replication of SARS-CoV-2. The extract of the basidial fungus Inonotus obliquus, which was being obtained by water extraction at a temperature of 50-95 °C for a period of 1.0 to 72 hours to be used to inhibit the replication of SARS-CoV-2, demonstrates 50% antiviral dose-dependent activity against SARS-CoV-2 during Vero E6 and Vero cell culture tests at a concentration ranging from 0.75 to 11.6 mcg/ml.

EFFECT: described above extract is effective for inhibiting the replication of SARS-CoV-2.

1 dwg, 1 tbl, 7 ex

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Authors

Teplyakova Tamara Vladimirovna

Pyankov Oleg Viktorovich

Skarnovich Maksim Olegovich

Bormotov Nikolaj Ivanovich

Kosogova Tatyana Alekseevna

Ovchinnikova Alena Sergeevna

Magerramova Anastasiya Viktorovna

Poteshkina Alevtina Leonidovna

Safatov Aleksandr Sergeevich

Filippova Ekaterina Igorevna

Dates

2021-01-28Published

2020-08-13Filed