FIELD: medicine and virology.
SUBSTANCE: invention relates to medicine and virology, namely to the use of the polyphenol complex of Amur maakia wood (PPC), the active substance of Maxar®, as an antiviral agent against SARS-CoV-2 coronavirus. The use of the polyphenolic complex of Amur maakia wood, the active substance of Maxar®, as an antiviral agent against SARS-CoV-2 coronavirus.
EFFECT: agent has low cytotoxic activity against Vero E6 cells and exhibits virus-inhibiting dose-dependent activity against SARS-CoV-2 in tests on Vero E6 cell culture, most effectively inhibits the replication of SARS-CoV-2 when directly exposed to the virus (virucidal effect).
1 cl, 2 dwg, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIVIRAL AGENT AGAINST HUMAN HERPESVIRUS TYPE I AND ENTEROVIRUS B | 2022 |
|
RU2798659C1 |
| 5'-O-(3-PHENYLPROPIONYL)-N4-HYDROXYCYTIDINE AND ITS APPLICATION | 2022 |
|
RU2791523C1 |
| METHOD FOR OBTAINING 5'-O-(3-PHENYLPROPIONYL)-N4-HYDROXYCYTIDINE | 2022 |
|
RU2791916C1 |
| METHOD FOR OBTAINING AN AQUEOUS EXTRACT OF FIREWEED LEAVES EPILOBIUM ANGUSTIFOLIUM L., WHICH EXHIBITS INHIBITORY ACTIVITY AGAINST SARS-CoV-2 CORONAVIRUS AND HERPES SIMPLEX VIRUS TYPE 2 IN VITRO | 2022 |
|
RU2788172C1 |
| SARS-CoV-2 CORONAVIRUS REPLICATION INHIBITOR BASED ON HUMIC SUBSTANCES | 2020 |
|
RU2752872C1 |
| URACIL DERIVATIVES WITH ANTIVIRAL ACTIVITY AGAINST SARS-COV-2 | 2021 |
|
RU2769828C1 |
| 3-BENZYL-5-METHYL-6-(PHENYLTHIO)-[1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7(3H)-ONE, WHICH HAS ANTIVIRAL ACTIVITY AGAINST THE SARS-CoV2 CORONAVIRUS | 2022 |
|
RU2808622C1 |
| SARS-COV-2 REPLICATION INHIBITOR BASED ON A WATER EXTRACT OF THE FUNGUS INONOTUS OBLIQUUS | 2020 |
|
RU2741714C1 |
| INDOLE-3-CARBOXYLIC ACID DERIVATIVE HAVING ANTIVIRAL ACTIVITY ON SARS-CoV-2 | 2022 |
|
RU2820633C1 |
| SARS-COV-2 CORONAVIRUS REPLICATION INHIBITOR BASED ON MELANIN FROM INONOTUS OBLIQUUS FUNGUS | 2020 |
|
RU2747018C1 |
