METHOD OF PRESERVATION OF A DONOR HEART Russian patent published in 2021 - IPC A01N1/02 A61K9/48 A61P9/04 

FIELD: biotechnology; preservation of a donor heart.

SUBSTANCE: method includes cannulation of the heart aorta, which is located in a cooled to +2-4℃ Krebs-Henseleit solution saturated with carbogen (95% O2 + 5% CO2), placing the distal end of the cannula above the level of the exit of the mouths of the coronary arteries. Then the cannula is fixed with a ligature and continuous insufflation of the coronary channel is performed, while the aortic valve moistened with oxygen is closed, at a constant pressure of 35 mm Hg at a volume rate of 3 ml/min for a period of up to 24 hours.

EFFECT: invention makes it possible to maintain the viability of the heart for 24 hours by providing continuous oxygenation of the donor heart in conditions of reducing its metabolic needs.

1 cl, 1 ex