COMPOSITION FOR THE PREVENTION OR TREATMENT OF NICOTINE ADDICTION, INCLUDING LIRIOPE PLATYPHYLLA EXTRACT AS THE ACTIVE INGREDIENT Russian patent published in 2021 - IPC A61K36/896 A61P25/30 

Abstract RU 2744268 C1

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to the pharmaceutical industry, namely to the use of a pharmaceutical composition including Liriope platyphylla root extract as an active ingredient for the prevention, treatment or mitigation of nicotine addiction, as well as to the use of a functional health product including Liriope platyphylla root extract as an active ingredient for the prevention, treatment or mitigation of nicotine addiction.

EFFECT: above-described applications of the pharmaceutical composition can reduce the expression of the tyrosine hydroxylase (TH) protein and return it to normal level, increase the expression of the dopamine transporter protein (DAT) and return it to normal levels, and suppress the phenomenon of nicotine dependence, which increases locomotor activity.

7 cl, 3 tbl, 3 ex, 8 dwg

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RU 2 744 268 C1

Authors

Seo, Joungwook

Ka, Minhan

Ryu, In Soo

Kim, Tae Wan

Lim, Ri Na

Lee, Dae Young

Lee, Young-Seob

Kim, Geum-Soog

Yoon, Dahye

Ban, Jae-Suk

Dates

2021-03-04Published

2020-06-05Filed