FIELD: immunology.
SUBSTANCE: present invention relates to the field of immunology. A method for obtaining a bispecific protein for binding two different types of proteins is proposed. In addition, a specific protein for binding two different types of proteins has been considered.
EFFECT: invention can find further application in obtaining bispecific proteins with increased degree of heterodimerization of constant Fc regions.
8 cl, 50 dwg, 38 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STABLE MULTI-SPECIFIC ANTIBODIES | 2018 |
|
RU2779602C2 |
| MOLECULES BINDING WITH CD38 AND PD-L1 | 2017 |
|
RU2764201C2 |
| IMMUNOCYTOKIN INCLUDING A HETERODIMERIC PROTEIN COMPLEX BASED ON ОСНОВЕ IL-15/IL-15Rα AND ITS APPLICATION | 2019 |
|
RU2753282C2 |
| MONOVALENT ASYMMETRIC BISPECIFIC ANTIBODIES WITH TANDEM FAB | 2017 |
|
RU2780591C2 |
| METHODS FOR QUANTITATIVE DETERMINATION OF POLYPEPTIDES | 2019 |
|
RU2782464C2 |
| CONSTRUCTED PAIRS OF HEAVY-LIGHT CHAINS OF IMMUNOGLOBULIN AND USE THEREOF | 2013 |
|
RU2826203C1 |
| ANTIBODIES BINDING TO GPRC5D | 2019 |
|
RU2797268C2 |
| BISPECIFIC ANTIBODIES TO HUMAN BETA-AMYLOID / HUMAN TRANSFERRIN RECEPTOR AND METHODS OF USING THEM | 2016 |
|
RU2730682C1 |
| ANTIBODIES TO CD38 AND COMBINATIONS WITH ANTIBODIES TO CD3 AND CD28 | 2018 |
|
RU2812910C2 |
| POLYPEPTIDE LINKER FOR PRODUCTION OF MULTI-SPECIFIC ANTIBODIES | 2018 |
|
RU2776302C2 |
