ANTI-CANCER VACCINES TARGETING PRAME AND THEIR APPLICATIONS Russian patent published in 2021 - IPC A61K38/00 

Abstract RU 2748903 C1

FIELD: biotech.

SUBSTANCE: invention relates to the field of biotechnology. The present invention discloses nucleic acid molecules containing one or more nucleic acid sequences that encode a mutated PRAME consensus antigen. Disclosed are vectors, compositions and vaccines containing one or more nucleic acid sequences that encode a mutated PRAME consensus antigen. Methods of treating a subject with a PRAME-expressing tumor and methods of preventing a PRAME-expressing tumor are disclosed. A mutated PRAME consensus antigen is disclosed.

EFFECT: methods of treating a PRAME-expressing tumor disclosed.

41 cl, 19 dwg, 7 tbl

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RU 2 748 903 C1

Authors

Yan, Jian

Slager, Anna

Garman, Bradley

Cooch, Neil

Dates

2021-06-01Published

2018-12-13Filed