SURVIVIN-TARGETED ANTI-CANCER VACCINES AND APPLICATIONS THEREOF Russian patent published in 2022 - IPC C07K14/47 A61K39/00 A61K48/00 A61P35/00 

Abstract RU 2776949 C2

FIELD: biotechnology.

SUBSTANCE: presented are a nucleic acid molecule encoding a synthetic consensus Survivin antigen (variants), a synthetic consensus Survivin antigen (variants), an expression vector, an immunogenic composition (variants), a vaccine for treating or preventing Survivin-expressing cancer, a method for treating a subject with a Survivin-expressing cancer cell, and a method for vaccinating a subject against a Survivin-expressing cancer cell.

EFFECT: production of safe and effective vaccines and methods for application thereof for preventing and/or treating cancer and reducing the mortality in subjects suffering from cancer.

22 cl, 14 tbl, 32 dwg, 5 ex

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RU 2 776 949 C2

Authors

Yan, Jian

Slager, Anna

Garman, Bradley

Cooch, Neil

Dates

2022-07-29Published

2018-12-13Filed