ANTICANCER VACCINES TARGETING BORIS AND METHODS OF THEIR APPLICATION Russian patent published in 2021 - IPC A61K39/39 A61K39/395 A61P35/00 

FIELD: biotech.

SUBSTANCE: invention relates to the field of biotechnology, namely to nucleic acid molecules that encode the brother of the regulator of imprinted sites (BORIS), an expression vector, BORIS, a vaccine for the treatment and/or prevention of a malignant tumor and treatment of a subject with a BORIS expressing cancer cell. The method includes administering a therapeutically effective amount of a vaccine that contains an effective amount of a vector containing a nucleic acid molecule encoding BORIS containing the amino acid sequence shown in amino acids 55-2040 of SEQ ID NO: 1 or 19-680 of SEQ ID NO: 2.

EFFECT: invention allows expanding the arsenal of technical means.

21 cl, 8 tbl, 9 dwg, 3 ex