FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine. A method for predicting the increased risk of developing chronic true eczema in men born and living in the Central Black Earth region of Russia, of Russian origin and not being relatives is proposed. DNA is isolated from peripheral venous blood. The FLG gene polymorphisms rs12130219, rs10888499, rs4363385 and rs12144049 are analyzed. A high risk of developing chronic true eczema is predicted in men with a combination of genotypes rs12130219 AA x rs10888499 AC x rs4363385 CT x rs12144049 TC of the FLG gene.
EFFECT: invention provides criteria for assessing the risk of developing chronic true eczema in men born and living in the Central Chernozem region of Russia, of Russian nationality and are not relatives, based on data on polymorphic loci rs12130219, rs10888499, rs4363385 and rs12144049 of the FLG gene.
1 cl, 4 dwg, 2 ex
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