FIELD: medicine.
SUBSTANCE: method involves sampling venous blood, recovering genomic DNA from the peripheral blood by polymerase chain reaction, analysing polymorphism of tumour necrosis factor α (TNFα), lymphotoxin α (Ltα) and tumour necrosis factor type 2 receptor (TNFR2) genes. The presence of -308A TNFα allele, or -308GA TNFα genotype, or +1663G TNFR2 allele, or a combination of -308A TNFα allele and +1663G TNFR2 allele, or a combination of -308A TNFα allele and +250G Ltα allele, or a combination of +250G Ltα allele and +1663G TNFR2 allele enables predicting a high risk of the sub-acute stage of chronic idiopathic eczema; the presence of -308GG TNFα genotype shows a low risk of the sub-acute stage of chronic idiopathic eczema.
EFFECT: developing the new criteria for the risk of the sub-acute stage of chronic idiopathic eczema.
7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION RISK OF CHRONIC TRUE ECZEMA DEVELOPMENT IN MALES | 2014 |
|
RU2574015C1 |
| METHOD FOR PREDICTING RISK OF DEVELOPING CHRONIC TRUE ECZEMA IN INDIVIDUALS DEPENDING ON AVAILABILITY OF FAMILY HISTORY | 2014 |
|
RU2585382C1 |
| METHOD FOR PREDICTION OF MODERATE SEVERITY OF CHRONIC TRUE ECZEMA | 2014 |
|
RU2578441C1 |
| METHOD FOR PREDICTION OF RISK OF STAGE III HYPERTENSIVE DISEASE IN PATIENTS WITH HYPERTENSION WITH METABOLIC SYNDROME | 2014 |
|
RU2598745C2 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING PRIMARY OPEN-ANGLE GLAUCOMA IN INDIVIDUALS DEPENDING ON PRESENCE/ABSENCE OF COMORBIDITY OF EYES | 2014 |
|
RU2597784C2 |
| METHOD FOR PREDICTION OF INTRAOCULAR PRESSURE LEVEL IN PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA DEPENDING ON GENETIC DATA | 2014 |
|
RU2580307C1 |
| METHOD FOR PREDICTING AN INCREASED RISK OF DEVELOPING CHRONIC TRUE ECZEMA IN MEN USING DATA ON FILAGGRIN GENE POLYMORPHISM | 2021 |
|
RU2750963C1 |
| METHOD FOR PREDICTING RISK OF DEVELOPING CHRONIC TRUE ECZEMA IN WOMEN, TAKING INTO ACCOUNT GENETIC FACTORS | 2021 |
|
RU2753274C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING PRIMARY OPEN-ANGLE GLAUCOMA STAGE III-IV | 2014 |
|
RU2580308C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING CHRONIC TRUE ECZEMA BASED ON MOLECULAR GENETIC DATA | 2021 |
|
RU2757936C1 |
