THREE-DIMENSIONAL POLYMER GRIDS WITH CHANNELS LOCATED IN THEM Russian patent published in 2021 - IPC C12Q1/68 B01J19/00 C12N11/08 G01N33/543 

Abstract RU 2752926 C2

FIELD: biotechnology.

SUBSTANCE: group of inventions is described, including a three-dimensional grid for determining the presence of the analyzed substance and/or the amount of the analyzed substance, an array containing the above-mentioned three-dimensional grid, a method for obtaining the three-dimensional grid, a method for obtaining the array, and a method for determining whether the analyzed substance is contained in a sample. In one embodiment, the three-dimensional grid consists of a polymer swollen in water, obtained by crosslinking the chains of a water-soluble polymer. The grid is crosslinked with the surface of a rigid substrate. The grid includes probe molecules covalently bound to the polymer chains, and the specified grid includes at least 5 channels that converge at a point in the inner part of the grid, so that the lateral distance between the channels decreases when moving from the surface to a point in the inner part.

EFFECT: invention expands the arsenal of means for determining the presence of the analyzed substance in the sample.

16 cl, 16 dwg, 3 ex

Similar patents RU2752926C2

Title Year Author Number
THREE-DIMENSIONAL POLYMER MESHES AND THEIR USE 2018
  • Klapproth Holger
  • Bednar Sonja
RU2780656C2
METHODS AND DEVICES FOR DETECTION AND IDENTIFICATION OF ENCODED GRANULES AND BIOLOGICAL MOLECULES 2007
  • Gorfinkel' Vera
  • Gorbovitski Boris
  • Gorbovitski Mikail
RU2487169C2
ANALYSIS OF MULTIPLE ANALYTES USING ONE ANALYSIS 2019
  • Stimers, Frenk Dzh.
  • Chzhan, Fan
  • Pokholok, Dmitrij K.
  • Norberg, Stiven
RU2824049C2
DIGITAL ANALYSIS OF MOLECULAR ANALYTES USING SINGLE MOLECULE DETECTION 2013
  • Staker Bryan P.
  • Liu Niandong
  • Staker Bart Lee
  • Mclaughlin Michael David
RU2670133C2
METHOD AND COMPOSITION FOR ANALYZING CELLULAR COMPONENTS 2016
  • Gunderson Kevin L.
  • Stimers Frenk Dzh.
  • Fisher Dzheffri S.
  • Rigatti Roberto
RU2717491C2
MODIFIED OLIGONUCLEOTIDE IMMOBILISATION ON A POLYMER SUBSTRATE BY PHYSICAL ADSORPTION 2015
  • Feitsma, Harma Martine
  • Lamberts, Inge
  • Kuijpers, Steven Paulus Lambertus
RU2732791C2
METHODS AND COMPOSITIONS FOR DETERMINING LIGANDS ON MATRICES USING INDICES AND BARCODES 2020
  • Segejl, Darren
  • Blek, Fiona E.
  • Brodin, Dzheffri Dennis
  • Berti, Lorentso
  • Leong, Syu Khong
  • Fisher, Dzheffri S.
  • Ekkhardt, Allen
  • Chzhan, Zhuj
  • Teo, In Nakh
RU2825578C1
COMPOSITIONS AND DETECTION METHODS 2008
  • Park Dehniel Dzh.
  • Kkhan Zakheer
  • Petter Karl F.
RU2480732C2
PLATFORM FOR DETECTING AND ANALYZING THERAPEUTIC AGENTS 2016
  • Khe Molli
  • Previt Majkl
  • Golynskij Misha
  • Kellinger Metyu Uilyam
  • Pejsadzhovich Serdzhio
  • Boutell Dzhonatan Mark
RU2724998C2
MULTIPLEX ANALYSES BASED ON APTAMERS 2013
  • Sanders Glenn
  • Kremer Stefan
  • Katilius Evaldas
RU2666989C2

RU 2 752 926 C2

Authors

Klapprot Kholger

Bednar Sonya

Dates

2021-08-11Published

2016-12-16Filed