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2 828 876

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IPC

C07D487/04(2006-01-01)

A61K31/4184(2006-01-01)

A61K31/4188(2006-01-01)

A61P31/04(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2023132995, 2023-12-13

(24)

Start date

2023-12-13

(22)

Actual filing date

2023-12-13

(45)

Published

2024-10-21

(72)

Inventor

Charushin Valerii NikolaevichIshmetova Rashida IrshotovnaGerasimova Natalia AvenirovnaEvstigneeva Natalia PetrovnaIgnatenko Nina KonstantinovnaKuznetsova Ekaterina AleksandrovnaBeliaev Danila VladimirovichVakhrusheva Diana VladimirovnaZilberberg Natalia VladimirovnaKungurov Nikolai VasilevichKrasnoborova Svetlana IurevnaRusinov Gennadii Leonidovich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Nauki Institut Organicheskogo Sinteza Im. I.Ia. Postovskogo Uralskogo Otdeleniia Rossiiskoi Akademii NaukNauchno-Issledovatelskii Institut Dermatovenerologii I Immunopatologii"Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Meditsinskii Issledovatelskii Tsentr Ftiziopulmonologii I Infektsionnykh Zabolevanii» Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

NOVEL ANTIBACTERIAL AGENT 3-(CARBOXYMETHYL)-1-(IMIDAZO[1,2-b][1,2,4,5]TETRAZIN-3-YL)-1H-BENZO[D]IMIDAZOLE-3-IUM CHLORIDE, ACTIVITY AGAINST NEISSERIA GONORRHOEAE AND MYCOBACTERIUM TUBERCULOSIS Russian patent published in 2024 - IPC C07D487/04 A61K31/4184 A61K31/4188 A61P31/04 A61P31/06

Abstract RU 2828876 C1

FIELD: pharmaceutical chemistry.

SUBSTANCE: invention relates to imidazo[1,2-b][1,2,4,5]tetrazine derivatives, specifically to 3-carboxymethyl-1-(imidazo[1,2-b][1,2,4,5]tetrazin-3-yl)-1H-benzo[d]imidazole-3-ium chloride, active against drug-sensitive and drug-resistant Neisseria gonorrhoeae and Mycobacterium tuberculosis.

EFFECT: obtaining 3-carboxymethyl-1-(imidazo[1,2-b][1,2,4,5]tetrazin-3-yl)-1H-benzo[d]imidazole-3-ium chloride, active against drug-sensitive and drug-resistant Neisseria gonorrhoeae and Mycobacterium tuberculosis.

1 cl, 2 ex, 1 tbl

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RU 2 828 876 C1

Authors

Charushin Valerii Nikolaevich

Ishmetova Rashida Irshotovna

Gerasimova Natalia Avenirovna

Evstigneeva Natalia Petrovna

Ignatenko Nina Konstantinovna

Kuznetsova Ekaterina Aleksandrovna

Beliaev Danila Vladimirovich

Vakhrusheva Diana Vladimirovna

Zilberberg Natalia Vladimirovna

Kungurov Nikolai Vasilevich

Krasnoborova Svetlana Iurevna

Rusinov Gennadii Leonidovich

Dates

2024-10-21—Published

2023-12-13—Filed