METHOD FOR FORMING A SILVER-CONTAINING BIOCOMPATIBLE COATING ON TITANIUM ALLOY IMPLANTS Russian patent published in 2021 - IPC A61L27/30 A61L27/06 A61F2/02 A61K33/38 C25D11/26 

FIELD: medical technology.

SUBSTANCE: invention relates to medical technology and reveals a method for applying a bioactive coating to titanium implants. The method for forming a silver-containing biocompatible coating on titanium implants consists in obtaining a coating by preliminary mechanical treatment of the titanium base, surface cleaning, chemical degreasing, an electrospray coating process followed by implantation of silver (Ag⁺) and copper (Cu⁺²) ions into it. After degreasing, the polished surface of the titanium base is first treated with an electric spark discharge with the introduction of carbon atoms into the titanium base. The introduction of carbon is carried out at a discharge energy of 0.1-0.35 J and a pulse duration of 60-110 microseconds in an argon medium. Then the treated surface of the titanium base is first treated with a beam of argon cluster ions (Ar⁺) with the introduction of argon ions into the titanium base and the formation of a porous structure on the surface of the titanium base. At the same time, the introduction of argon cluster ions is carried out with an energy of 30-50 keV, fluence 5⋅10¹⁶-2⋅10¹⁷ cm-² with the direction of the argon ion beam at an angle of 40-60 degrees to the normal to the irradiated surface. Then the formed porous structure is treated with a beam of silver (Ar⁺) and copper (Cu⁺²) ions with the introduction of (Ar⁺) and copper (Cu⁺²) ions into the formed porous structure of the surface of the titanium base to form an ion-doped layer with antimicrobial properties. At the same time, implantation of silver and copper ions is carried out using an implanter cathode made of Cu-Ag system material with a silver content of 22-45, wt. %, with an energy of 30-50 keV and irradiation fluence (5-9.2) ⋅10¹⁷ cm^-2.

EFFECT: increase in the osseointegration properties of intraosseous titanium implants by creating a silver-containing biocompatible coating with antimicrobial properties without a boundary between the coating and the implant surface with a high duration of silver ions entering the biological solution.

1 cl, 10 dwg, 3 tbl, 3 ex