FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to a method for selecting T-cell receptor (hereinafter – TCR). The proposed method includes the attachment of a drop barcode-labeled polynucleotide to an oligonucleotide part of a molecule of pMHC-oligonucleotide conjugate in a drop and TCR polynucleotide of an isolated T-cell of a set of T-cells.
EFFECT: proposed method allows for the identification of isolated T-cells for their subsequent sequencing.
93 cl, 21 dwg, 1 tbl, 22 ex
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Authors
Dates
2021-12-30—Published
2017-01-12—Filed