METHOD FOR PREDICTION OF BACTERIAL VAGINOSIS RECURRENCES Russian patent published in 2022 - IPC G01N33/569 G01N33/58 C12Q1/6806 C12Q1/6844 C12Q1/6883 C12Q1/689 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to clinical laboratory diagnostics, medical microbiology, obstetrics and gynecology. A method for predicting recurrences of bacterial vaginosis (BV) is proposed. The vaginal biotope is examined by real-time PCR using a set of reagents DNA-sorb-AM. The DNA concentrations of Gardnerella vaginalis genotypes 1, 2, 4 are determined. The probability of developing BV is calculated using the following formulas: Z=-12.58+0.49×X₁+1.04×X₂+0.95×X₃+0.78×X₄, Y=-3.32-0.26×X₁-0.04×X₂+0,03×X₃+1.46×X₄, where Z is the likelihood of recurrent BV; Y is the probability that recurrent BV will not develop. At Z>Y, the development of BV relapses is predicted with a probability of 84%. With Z<Y, with a 95% probability, recurrent BV will not develop.

EFFECT: invention provides the development of a method for predicting recurrent BV with a high degree of prediction accuracy.

1 cl, 2 ex