METHOD FOR PREPARING PORCINE DERMIS FOR CREATING ACELLULAR DERMAL MATRIX IN EXPERIMENT Russian patent published in 2022 - IPC G09B23/28 A61B17/00 A61B17/322 A61L27/36 

Abstract RU 2768156 C1

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine, namely to regenerative medicine, plastic surgery. On the side surface of a pig at age of 3.5–6 months, section of 20–25 × 60–70 cm is marked. Single sample of a full-thickness skin flap is cut. Sample is uniformly placed on the roller; the flap is stretched with Kocher clamps. Epidermal layer is removed using a dermatome. Then, using a disk knife with diameter of 100 mm with the condition of its perpendicular position relative to the flap surface, 1–3 derma samples are cut out for a matrix with size of 10±0.5 × 20 cm and thickness of 0.7 mm.

EFFECT: method enables to obtain samples without epidermis, with precisely specified thickness and dimensions, which provides further production of high-quality acellular dermal matrix (ADM) with optimal characteristics for use as a fixing material in reconstructive plastic surgery.

1 cl, 4 ex

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RU 2 768 156 C1

Authors

Melkonyan Karina Igorevna

Sotnichenko Aleksandr Sergeevich

Verevkin Aleksandr Aleksandrovich

Rusinova Tatyana Viktorovna

Asyakina Alevtina Sergeevna

Kozmaj Yana Andreevna

Dates

2022-03-23Published

2021-05-31Filed