METHOD FOR PREDICTION OF AGGRESSIVE FORMS OF PROSTATE CANCER IN PATIENTS OF INTERMEDIATE AND HIGH RISK GROUP Russian patent published in 2022 - IPC G01N33/50 C12Q1/6855 C12Q1/6886 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and aims at predicting aggressive forms of prostate cancer in intermediate and high-risk patients. Biopsy or postoperative tumour samples are analysed by multiplex analysis of ligated samples to detect deletions of PTEN and RB1 genes. If detecting PTEN gene deletions, perineural invasion and lymph node involvement are predicted. If observing RB1 gene deletions, low tumour differentiation, presence of a cribriform component of growth, invasion of periprostatic fat and affection of lymph nodes are predicted.

EFFECT: invention provides higher accuracy of predicting aggressive forms of prostate cancer and specifying the therapeutic approach.

1 cl, 4 ex