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2 675 695

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IPC

A61K31/00(2006-01-01)

A61K31/45(2006-01-01)

A61K31/133(2006-01-01)

A61K31/16(2006-01-01)

A61K31/4425(2006-01-01)

(21) (22)

Application

2018108218, 2018-03-06

(24)

Start date

2018-03-06

(22)

Actual filing date

2018-03-06

(45)

Published

2018-12-24

(72)

Inventor

Nosov Aleksandr KonstantinovichReva Sergej AleksandrovichPetrov Sergej BorisovichProtsenko Svetlana AnatolevnaBerkut Mariya VladimirovnaBuevich Natalya Nikolaevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Onkologii Imeni N.N. Petrova" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

METHOD OF TREATING THE PROSTATIC GLAND CANCER OF A HIGH AND A VERY HIGH RISK Russian patent published in 2018 - IPC A61K31/00 A61K31/45 A61K31/133 A61K31/16 A61K31/4425

Abstract RU 2675695 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncourology, and can be used for the treatment of prostatic gland cancer (PGC) of a high and a very high risk. To this purpose, in a neoadjuvant regimen, a complex chemohormonal therapy is carried out according to the docetaxel regimen at a dose of 75 mg/m² intravenously 1 time in 21 days, only 6 injections and hormonal drug degarelix at a dose of 240 mg subcutaneously, then every 28 days in a maintenance dose of 80 mg, only 6 injections.

EFFECT: method allows to increase the efficiency of treatment of patients with a high and a very high risk of PGC, reduce the volume of the prostatic gland, significantly reduce the PSA level, increase the effectiveness of the subsequent RPE.

1 cl, 3 ex

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RU 2 675 695 C1

Authors

Nosov Aleksandr Konstantinovich

Reva Sergej Aleksandrovich

Petrov Sergej Borisovich

Protsenko Svetlana Anatolevna

Berkut Mariya Vladimirovna

Buevich Natalya Nikolaevna

Dates

2018-12-24—Published

2018-03-06—Filed