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IPC

A61B10/00(2006-01-01)

G01N33/48(2006-01-01)

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Application

2015155927, 2015-12-25

(24)

Start date

2015-12-25

(22)

Actual filing date

2015-12-25

(45)

Published

2017-03-28

(72)

Inventor

Sergeeva Natalya SergeevnaGitis Valentin GrigorevichYurkov Evgenij FilippovichPirogov Sergej AnatolevichKaprin Andrej DmitrievichAlekseev Boris YakovlevichSkachkova Tatyana EvgenevnaMarshutina Nina ViktorovnaMustafin Aleksandr Gazizovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Radiologicheskij Tsentr" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Minzdrava Rossii)Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Problem Peredachi Informatsii Im. A.A. Kharkevicha Rossijskoj Akademii Nauk Ran)Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Rossijskij Natsionalnyj Issledovatelskij Meditsinskij Universitet Imeni N.I. Pirogova Minzdrava Rossii Vpo Rnimu Im. N.I. Pirogova Minzdrava Rossii)

METHOD FOR PROSTATE CANCER STAGE AND AGGRESSIVENESS PREDICTION PRIOR TO SURGERY, BASED ON LABORATORY AND CLINICAL PARAMETERS Russian patent published in 2017 - IPC A61B10/00 G01N33/48

Abstract RU 2614501 C1

FIELD: medicine.

SUBSTANCE: levels of comPSA, svPSA, [-2]proPSA are determined in the patient's blood serum prior to treatment. Patient's age is determined. The Prostate Health Index is calculated. Point values are assigned for Gr.i.Gleason and Gr.T indices. The Gleason index (APHIG index) for the prostate cancer is calculated by the stated formula. If APHIG < 3.6 units, indolent localized prostate cancer is diagnosed, Gleason index is ≤ 6. If APHIG > 5.0 units, aggressive prostate cancer is diagnosed, Gleason index > 6 or ≥ T3a stage. If APHIG > 6.0 units, aggressive prostate cancer is diagnosed, Gleason index > 6 and ≥ T3a stage.

EFFECT: method provides more reliable estimation of the tumour stage for patients with prostate cancer, avoids hyper- and underdiagnosis, improves long-term outcomes due to complex evaluation of the most significant indicators.

3 dwg, 4 tbl, 3 ex

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RU 2 614 501 C1

Authors

Sergeeva Natalya Sergeevna

Gitis Valentin Grigorevich

Yurkov Evgenij Filippovich

Pirogov Sergej Anatolevich

Kaprin Andrej Dmitrievich

Alekseev Boris Yakovlevich

Skachkova Tatyana Evgenevna

Marshutina Nina Viktorovna

Mustafin Aleksandr Gazizovich

Dates

2017-03-28—Published

2015-12-25—Filed