FIELD: pharmaceutics.
SUBSTANCE: invention relates to heteroaromatic compounds. A compound of the formula (I) or its pharmaceutically acceptable salt is proposed, where X is CH or N; Y is N, and Z is C; or Y is C, and Z is N; 5-element ring containing N, Y and Z is heteroaromatic ring; ring A is phenyl or 5- or 6-element heteroaryl having one heteroatom independently selected from N and S; m is 0 or 1; each R1 is independently selected from halogen, C1-C6 alkyl, R2O, R3S(O)2, R4S(O)2N(R5), and R13R14NS(O)2; each of R2, R3, R4, R5, and R13 is independently selected from H and C1-C6 alkyl; R14 is H; and any alkyl is substituted with one or more F, if necessary. A pharmaceutical composition, the use of a compound, and a method for the treatment of enterovirus infection are also proposed.
EFFECT: production of compounds that can act as a PI4 kinase inhibitor and have antiviral activity.
16 cl, 6 dwg, 10 tbl
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