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2 772 904

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IPC

C12N15/09(2006-01-01)

(21) (22)

Application

2021136723, 2021-12-13

(24)

Start date

2021-12-13

(22)

Actual filing date

2021-12-13

(45)

Published

2022-05-26

(72)

Inventor

Toropovskii Andrei NikolaevichViktorov Denis AleksandrovichShcherbakov Dmitrii NikolaevichNikitin Aleksei Georgievich

(73)

Holder

Obshchestvo S Ogranichennoi Otvetstvennostiu Dzhi»/ Ooo Dzhi"

RECOMBINANT PLASMID PVBL-RBDDELTA PROVIDING SYNTHESIS AND SECRETION OF THE RECOMBINANT RECEPTOR-BINDING DOMAIN (RBD) OF THE SARS-COV-2 CORONAVIRUS LINE B.1.617.2 IN MAMMALIAN CELLS Russian patent published in 2022 - IPC C12N15/09

Abstract RU 2772904 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. Described is the plasmid pVBL-RBDdelta containing a nucleotide sequence encoding the SARS-CoV-2-line B.1.617.2 RBD protein and providing expression of this RBD protein in mammalian cells and further purification by affinity chromatography. The resulting RBD protein is intended for the direct production of a vaccine preparation against SARS-CoV-2-line B.1.617.2.

EFFECT: invention expands the arsenal of agents for the treatment of coronavirus infection.

1 cl, 1 dwg, 1 tbl, 4 ex

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RU 2 772 904 C1

Authors

Toropovskii Andrei Nikolaevich

Viktorov Denis Aleksandrovich

Shcherbakov Dmitrii Nikolaevich

Nikitin Aleksei Georgievich

Dates

2022-05-26—Published

2021-12-13—Filed