FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely phthisiology and urology, and can be used to simulate kidney tuberculosis in an experiment. The method involves the introduction of a culture of tuberculosis mycobacterium into the cortical layer of the kidney. At the same time, a fine needle puncture of the cortical layer of the parenchyma of the lower pole of the kidney is performed under ultrasound control to the rabbit, after which a suspension of a standardized strain of M. tuberculosis H37Rv is injected through a puncture needle in a dose of 106 microbial cells in 0.2 ml of saline solution.
EFFECT: invention provides for the creation of an experimental model close to the clinical course of the disease, using minimally invasive surgical intervention and reducing the risk of postoperative complications.
1 cl, 6 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD OF MODELING COMBINED PATHOLOGY OF LUNG CARCINOMA AND TUBERCULOSIS | 2022 |
|
RU2800964C1 |
METHOD OF MODELING DESTRUCTIVE HEPATIC TUUBERCULOSIS | 0 |
|
SU1443019A1 |
METHOD FOR MODELING TUBERCULOSIS OF FEMALE GENITAL ORGANS | 2015 |
|
RU2600926C2 |
RECOMBINANT INFLUENZA VIRUS STRAINS EXPRESSING MYCOBACTERIAL PROTECTIVE ESAT-6 ANTIGEN AND USES THEREOF IN TUBERCULOSIS TREATMENT AND PROPHYLAXIS | 2005 |
|
RU2318872C2 |
METHOD FOR INACTIVATION OF DRUG-SENSITIVE AND DRUG-RESISTANT STRAINS OF MYCOBACTERIUM TUBERCULOSIS IN EXPERIMENTAL CONDITIONS IN VITRO | 2018 |
|
RU2702646C1 |
METHOD OF MODELLING MALE GENITAL TUBERCULOSIS | 0 |
|
SU1532970A1 |
INACTIVATED MYCOBACTERIA FOR ORAL USE IN THE PREVENTION OF TUBERCULOSIS | 2013 |
|
RU2657753C2 |
WAY OF MODELLING OF ACUTE PYELONEPHRITIS | 2008 |
|
RU2363055C1 |
VACCINE AGAINST TUBERCULOSIS | 2017 |
|
RU2647831C1 |
AGENT WHICH POTENTIATES ANTITUBERCULOUS ACTION OF ISONIAZIDE | 1980 |
|
RU2045278C1 |
Authors
Dates
2022-07-13—Published
2021-07-14—Filed