FIELD: pharmaceutical industry.
SUBSTANCE: inventions group relates to medicine and the pharmaceutical industry and can be used for the treatment or prevention of bacterial infectious diseases. The inhaled pharmaceutical composition for the treatment or prevention of bacterial infectious diseases includes lauryl dimethylamine oxide, polyethylene glycol, chlorhexidine base, amino acid and deionized water in the following ratio, wt.%: lauryl dimethylamine oxide 0.003 - 0.000003; polyethylene glycol 0.002 - 0.000002; chlorhexidine base 0.001 - 0.000001; amino acid 0.002 - 0.000002; deionized water up to 100. Also proposed is the use of the specified composition for the treatment and prevention of bacterial infectious diseases, including ventilator-associated pneumonia, cystic pulmonary fibrosis and chronic obstructive pulmonary disease, and a method for obtaining the specified composition, including the stages of sequential mixing of the components in the order of deionized water, lauryl dimethylamine oxide, polyethylene glycol, chlorhexidine base , amino acid.
EFFECT: synergistic antibacterial effect is provided, which allows highly diluted compositions to exhibit high antibacterial activity.
5 cl, 6 dwg, 4 tbl, 4 ex
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Authors
Dates
2022-08-01—Published
2022-05-24—Filed