CATIONIC LIPIDS Russian patent published in 2022 - IPC C07C229/12 A61K31/7088 A61K31/7105 A61K47/18 A61K48/00 A61K9/16 

Abstract RU 2782218 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to a method, which allows for introduction of active ingredients, in particular nucleic acids, into cells with better efficiency; and to cationic lipids, etc. for use in this method. A new compound corresponds to the formula (I), in which n is an integer from 2 to 5, R is a linear C1-5 alkyl group, linear C7-11 alkenyl group, or linear C11 alkadienyl group, and wavy lines in each case are independently a cis-bond or trans-bond, or its pharmaceutically acceptable salt.

EFFECT: obtaining cationic lipids.

8 cl, 7 tbl, 11 ex

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RU 2 782 218 C2

Authors

Matsumoto, Satoru

Omori, Yoshimasa

Mineno, Masahiro

Hoashi, Yasutaka

Dates

2022-10-24Published

2018-12-27Filed