FIELD: biotechnology.
SUBSTANCE: present invention relates to a method, which allows for introduction of active ingredients, in particular nucleic acids, into cells with better efficiency; and to cationic lipids, etc. for use in this method. A new compound corresponds to the formula (I), in which n is an integer from 2 to 5, R is a linear C1-5 alkyl group, linear C7-11 alkenyl group, or linear C11 alkadienyl group, and wavy lines in each case are independently a cis-bond or trans-bond, or its pharmaceutically acceptable salt.
EFFECT: obtaining cationic lipids.
8 cl, 7 tbl, 11 ex
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Authors
Dates
2022-10-24—Published
2018-12-27—Filed