CATIONIC LIPIDS Russian patent published in 2022 - IPC C07C229/12 A61K31/7088 A61K31/7105 A61K47/18 A61K48/00 A61K9/16

Abstract RU 2782218 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to a method, which allows for introduction of active ingredients, in particular nucleic acids, into cells with better efficiency; and to cationic lipids, etc. for use in this method. A new compound corresponds to the formula (I), in which n is an integer from 2 to 5, R is a linear C_1-5 alkyl group, linear C_7-11 alkenyl group, or linear C₁₁ alkadienyl group, and wavy lines in each case are independently a cis-bond or trans-bond, or its pharmaceutically acceptable salt.

EFFECT: obtaining cationic lipids.

8 cl, 7 tbl, 11 ex

Similar patents RU2782218C2

Title	Year	Author	Number
CATIONIC LIPID	2019	Matsumoto, Satoru Omori, Yoshimasa Mineno, Masahiro Sawai, Yasuhiro Kakimoto, Nozomu Hoashi, Yasutaka	RU2784335C2
TRIALKYL CATIONIC LIPIDS AND METHODS FOR USING THEM	2013	Khejs Dzhejms Vud Mark Martin Alan	RU2718053C2
CATIONIC LIPID	2017	Sudzuki Yuta Takakhasi Josinori	RU2740921C2
LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS	2013	Pejn Dzhozef I. Godett Dzhon A. Khou Zheng Akhmadian Mokhammed Ju Lej Knopov Viktor Akopyan Violetta Karmali Prija Vitte Richard P. Safarzadekh Neda Jing Venbin Zhang Jun	RU2658007C2
METHOD OF T-CELL ACTIVATION/PROLIFERATION	2019	Kuwae, Shinobu Matsumoto, Satoru Hayashi, Akira Kassai, Yoshiaki Nakayama, Kazuhide	RU2806549C2
IONIZABLE LIPIDS AND COMPOSITIONS THEREOF IN FORM OF NANOPARTICLES	2020	Stenton, Mettyu G. Nolting, Bert Fejnshtejn, Gregori Leblan, Mishel Chetterton, Dzhon Edvard	RU2836646C1
COMPOUNDS FOR TARGETED DRUG DELIVERY AND ENHANCING siRNA ACTIVITY	2012	Shridkhar K. Negerajyan Karmeli Priya Niitsu Joshiro Pejn Dzhozef I. Khou Dzeng Gaudette Dzhon A. Knopov Viktor Uitt Richard P. Akhmadian Mukhammed Perelman Loren A. Tanaka Yasunobu Akopyan Violetta	RU2769872C2
ANTICANCER RNA VACCINES	2017	Valiante, Nicholas Ashburn, Ted Hopson, Kristen	RU2768829C2
COMPOUNDS FOR TARGETED DELIVERY OF MEDICINE AND ENHANCED SIPHK ACTIVITY	2012	Shridkhar K. Negerajyan Karmeli Priya Niitsu Joshiro Pejn Dzhozef I. Khou Dzeng Gaudette Dzhon A. Knopov Viktor Uitt Richard P. Akhmadian Mukhammed Perelman Loren A. Tanaka Yasunobu Akopyan Violetta	RU2632888C2
POLYNUCLEOTIDES CODING INTERLEUKIN-12 (IL12), AND APPLICATIONS THEREOF	2017	Frederick, Joshua Hewitt, Susannah Bai, Ailin Hoge, Stephen Presnyak, Vladimir Mcfadyen, Iain Benenato, Kerry Kumarasinghe, Ellalahewage Sathyajith	RU2769316C2

RU 2 782 218 C2

Authors

Matsumoto, Satoru

Omori, Yoshimasa

Mineno, Masahiro

Hoashi, Yasutaka

Dates

2022-10-24—Published

2018-12-27—Filed