METHOD FOR TREATMENT OF MYCOTIC CORNEAL ULCERS Russian patent published in 2022 - IPC A61F9/01 A61K31/7036 A61K31/197 A61K31/525 A61P27/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to ophthalmology, and can be used in the complex treatment of patients with mycotic corneal ulcers. The method includes crosslinking. With mycotic ulcers of the cornea, Tobramycin 0.3%, Corneregel 5%, Balarpan 0.01% 1 drop 4 times a day, Bromfenac 0.09% 1 drop 1 time a day are instilled from the first day of treatment for 7 days, Fluconazole 0.2% is administered intravenously 200 mg 2 times a day for 3 days from the first day of treatment, starting from the fourth day from the beginning of treatment, 200 mg 1 time a day for 4 days. On day 8, crosslinking is carried out with instillation of antimycotic agents, then the cornea is irradiated with ultraviolet light, during irradiation, instillations of the Dextralink solution are carried out with simultaneous instillation of antimycotic agents. The operation is completed by applying a soft contact lens, in the early postoperative period, instillations are prescribed for 14 days: Tobramycin 0.3%, Fluconazole 0.2%, Corneregel 5%, Systane-ultra, Hylo-max Comod, Balarpan 0.01%. After UV-crosslinking, dynamic observation is carried out with monthly monitoring of the thickness of the cornea using OCT, and with opacity less than 2/3 of the cornea, anterior layered keratoplasty is performed, and with opacity more than 2/3, through keratoplasty is performed.

EFFECT: use of the invention makes it possible to enhance the antifungal effect with an increase in the rate of resorption and purification of the ulcer, accelerate the healing of corneal ulcers, prevent its recurrence, as well as reduce the likelihood of emergency keratoplasty and improve conditions for possible subsequent keratoplasty.

1 cl, 2 ex