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2 784 350

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IPC

A61K31/44(2006-01-01)

A61P27/02(2006-01-01)

G09B23/28(2006-01-01)

(21) (22)

Application

2022110058, 2022-04-14

(24)

Start date

2022-04-14

(22)

Actual filing date

2022-04-14

(45)

Published

2022-11-23

(72)

Inventor

Solovev Nikolaj VadimovichPobeda Anna SergeevnaSkachilova Sofiya YakovlevnaGureev Vladimir VladimirovichSimakina Ekaterina AleksandrovnaYurochkina Aleksandra MikhajlovnaPeresypkina Anna AleksandrovnaBashuk Viktoriya VladimirovnaPokrovskij Mikhail VladimirovichProskurina Oksana VladimirovnaShilova Elena VladimirovnaChernyaeva Sofya SergeevnaKostina Darya AleksandrovnaKochkarova Indira SultanovnaEfimenko Svetlana VladimirovnaLebedeva Darya Sergeevna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Natsionalnyj Issledovatelskij Universitet"

METHOD FOR CORRECTING MICROCIRCULATORY DISORDERS WITH 2-ETHYL-6-METHYL-3-HYDROXYPYRIDINIUM 5-HYDROXY-3-PYRIDINOCARBONATE IN EXPERIMENTAL NMDA-MEDIATED EXCITOTOXICITY IN THE RETINA Russian patent published in 2022 - IPC A61K31/44 A61P27/02 G09B23/28

Abstract RU 2784350 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to experimental pharmacology and ophthalmology. Intramuscular injection of 2-ethyl-6-methyl-3-hydroxypyridinium 5-hydroxy-3-pyridinocarbonate at a dose of 25.5 mg/kg is performed 60 minutes after modeling excitotoxic damage to the retina. Then daily administration is performed once a day for 7 days.

EFFECT: invention provides pronounced correction of retinal microcirculatory disorders.

1 cl, 1 tbl, 1 ex

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RU 2 784 350 C1

Authors

Solovev Nikolaj Vadimovich

Pobeda Anna Sergeevna

Skachilova Sofiya Yakovlevna

Gureev Vladimir Vladimirovich

Simakina Ekaterina Aleksandrovna

Yurochkina Aleksandra Mikhajlovna

Peresypkina Anna Aleksandrovna

Bashuk Viktoriya Vladimirovna

Pokrovskij Mikhail Vladimirovich

Proskurina Oksana Vladimirovna

Shilova Elena Vladimirovna

Chernyaeva Sofya Sergeevna

Kostina Darya Aleksandrovna

Kochkarova Indira Sultanovna

Efimenko Svetlana Vladimirovna

Lebedeva Darya Sergeevna

Dates

2022-11-23—Published

2022-04-14—Filed