METHOD FOR PREVENTING EXCITOTOXIC DAMAGE OF RETINA BY DIMETHYLAMINOETHANOL DERIVATIVE IN EXPERIMENT Russian patent published in 2022 - IPC G09B23/28 A61K31/137 A61P27/02 

Abstract RU 2765675 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to experimental pharmacology, and can be used for correction of excitotoxic retinal damage. Method of excitotoxic retinal injury correction involves intragastric administration of bis-(-2-hydroxyethyl-N-dimethylaminium) 2[(2.6-dichlorophenyl)amino]-phenylethanoate — DMAE 10-19 single dose of 13.8 mg/kg white Wistar rats 40 minutes before simulating excitotoxic retinal injury.

EFFECT: invention provides an effective method for correcting excitotoxic retinal damage.

1 cl, 1 tbl, 1 ex

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RU 2 765 675 C1

Authors

Pobeda Anna Sergeevna

Pokrovskij Mikhail Vladimirovich

Solovev Nikolaj Vadimovich

Skachilov Sofiya Yakovlevna

Gureev Vladimir Vladimirovich

Semakina Ekaterina Aleksandrovna

Yurochkina Aleksandra Mikhajlovna

Peresypkina Anna Aleksandrovna

Bolgova Evgeniya Vitalevna

Proskurina Oksana Vladimirovna

Shilova Elena Vladimirovna

Pokrovskij Vladimir Mikhajlovich

Patrakhanov Evgenij Aleksandrovich

Puchenkova Olesya Andreevna

Martynova Olga Viktorovna

Tsuverkalova Yuliya Mikhajlovna

Dates

2022-02-01Published

2021-06-22Filed