FIELD: biology; chemistry.
SUBSTANCE: group of inventions relates to the field of biological and chemical researches. A flow cell is disclosed, containing a base; a selectively removable self-assembled porous molecular mesh located on the base, defining a pattern of open sections of the base; and a nano-structure located at least on some of open sections, and polymerase attached to the nano-structure. The nano-structure is an electroconductive channel including material selected from a group consisting of a conductor and a semiconductor, and it has a geometrical shape selected from a group consisting of a tube, wire, and band, where the selectively removable self-assembled porous molecular mesh is a planar supra-molecular mesh of amine and diimide. A sequencing system and a method for the production of the above-mentioned flow cell are also disclosed.
EFFECT: group of inventions provides improved specificity of attachment of biomolecules and better sensitivity of sensors.
13 cl, 11 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| FLOW-THROUGH CELLS WITH HYDROGEL COATING | 2018 |
|
RU2751517C2 |
| AMPLIFICATION OF NUCLEIC ACID LIBRARIES USING KINETIC EXCLUSION | 2017 |
|
RU2759690C2 |
| RESIN COMPOSITION AND FLOW CELLS INCLUDING THIS RESIN COMPOSITION | 2019 |
|
RU2778014C1 |
| PROTECTIVE SURFACE COATING FOR FLOW CELLS | 2018 |
|
RU2729688C1 |
| BIOCHIP INCLUDING SEQUENCING PRIMER AND NON-SEQUENCING UNIT | 2017 |
|
RU2765075C2 |
| RESINOUS COMPOSITION AND FLOW CELLS INCLUDING SAID RESINOUS COMPOSITION | 2019 |
|
RU2773387C1 |
| MODULATION OF POLYMER GRANULES FOR DNA PROCESSING | 2019 |
|
RU2822154C2 |
| METHODS FOR ENCAPSULATING SINGLE CELLS, ENCAPSULATED CELLS, AND METHODS OF APPLICATION THEREOF | 2019 |
|
RU2750567C2 |
| METHODS OF ENCAPSULATING SINGLE CELLS, THE ENCAPSULATED CELLS AND USES THEREOF | 2019 |
|
RU2793717C2 |
| FLOW CELLS AND SEQUENCING KITS | 2019 |
|
RU2823075C2 |
