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2 718 671

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IPC

G09B23/28(2006-01-01)

(21) (22)

Application

2019124739, 2019-08-01

(24)

Start date

2019-08-01

(22)

Actual filing date

2019-08-01

(45)

Published

2020-04-13

(72)

Inventor

Kit Oleg IvanovichFrantsiyants Elena MikhajlovnaKaplieva Irina ViktorovnaSurikova Ekaterina IgorevnaTrepitaki Lidiya KonstantinovnaNeskubina Irina ValerevnaLesovaya Natalya Sergeevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Onkologii" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

METHOD FOR REVERSING GENETICALLY DETERMINED INHIBITION OF GROWTH OF A MALIGNANT TUMOR IN EXPERIMENT Russian patent published in 2020 - IPC G09B23/28

Abstract RU 2718671 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental studies in oncology. C57BL/6-PlautmI.IBug-ThisPlau6FDhu/GFDhu mice, which are knocked out by the urokinase-uPA gene, are reproduced with chronic neurogenic pain by sciatic ligation of both sides. 2 weeks later, suspension of tumor cells of mouse melanoma B16/F10 in physiological saline is introduced subcutaneously under the blade.

EFFECT: method enables eliminating genetically determined inhibition of B16/F10 melanoma and enables studying the tumor pathogenesis.

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RU 2 718 671 C1

Authors

Kit Oleg Ivanovich

Frantsiyants Elena Mikhajlovna

Kaplieva Irina Viktorovna

Surikova Ekaterina Igorevna

Trepitaki Lidiya Konstantinovna

Neskubina Irina Valerevna

Lesovaya Natalya Sergeevna

Dates

2020-04-13—Published

2019-08-01—Filed